Acetazolamide May Improve AHI in Obstructive and Central Sleep Apnea

Patients with either obstructive or central sleep apnea experienced improvements in apnea hypopnea index (AHI) following treatment with acetazolamide, according to the results of a meta-analysis published in the journal CHEST.

The study authors searched MEDLINE, EMBASE and ClinicalTrials.gov for studies in which adults with obstructive or central sleep apnea received oral acetazolamide vs no acetazolamide (control). Improvements in AHI and oxygen saturation nadir were compared between groups for both types of sleep apnea.

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